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GHS pictogram GHS06

Skull and Crossbones Pictogram (GHS06)

GHS pictogram GHS06: Skull and Crossbones

Acute toxicity (fatal or toxic) by swallowing, skin contact or inhalation — GHS Categories 1–3.

  • GHS06
  • Symbol: Skull and crossbones
  • Danger

Hazards this pictogram covers

  • Acute toxicity, oral (Categories 1–3)
  • Acute toxicity, dermal (Categories 1–3)
  • Acute toxicity, inhalation (Categories 1–3)

Hazard classes and hazard statements

Based on the GHS classification table, GHS06 is assigned to these hazard classes and hazard statements.

Hazard classCategoriesHazard statements
Acute toxicity, oralCategory 1, 2; Category 3H300, H301
Acute toxicity, dermalCategory 1, 2; Category 3H310, H311
Acute toxicity, inhalationCategory 1, 2; Category 3H330, H331
Acute toxicity, oral; acute toxicity, dermalCategory 1, 2; Category 3H300+H310, H301+H311
Acute toxicity, oral; acute toxicity, inhalationCategory 1, 2; Category 3H300+H330, H301+H331
Acute toxicity, dermal; acute toxicity, inhalationCategory 1, 2; Category 3H310+H330, H311+H331
Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalationCategory 1, 2; Category 3H300+H310+H330, H301+H311+H331

Typical precautions

These precautionary statements are the ones most often called for by hazards that carry GHS06. The right set for a product depends on its classification.

  • P405: Store locked up.
  • P501: Dispose of contents/container to ...
  • P321: Specific treatment (see ... on this label).
  • P264: Wash hands [and ...] thoroughly after handling.
  • P270: Do not eat, drink or smoke when using this product.
  • P316: Get emergency medical help immediately.
  • P262: Do not get in eyes, on skin, or on clothing.
  • P271: Use only outdoors or in a well-ventilated area.

Chemicals carrying GHS06

28 chemicals in our database. Classification comes from each chemical's primary GHS source, so a supplier's SDS may differ.

GHS06 frequently asked questions

What does the skull and crossbones pictogram (GHS06) mean?

Acute toxicity (fatal or toxic) by swallowing, skin contact or inhalation — GHS Categories 1–3. It is one of the nine GHS hazard pictograms and appears as a black skull and crossbones symbol on a white background inside a red diamond border.

Which hazard statements use GHS06?

GHS06 appears with 14 current hazard statements, including H300, H301, H310, H311, H330, H331, H300+H310, H300+H330. The full list is on this page.

What signal word goes with GHS06?

GHS06 is used with the signal word "Danger", depending on the hazard category.

A pictogram shows the type of hazard, not its severity. Read the signal word, hazard statements and the supplier's SDS.

https://pubchem.ncbi.nlm.nih.gov/ghs/ghscode_10.txt (UN GHS Revision 10, retrieved 2026-10-12)